Genzo Iguchi Selected Research

Immune Checkpoint Inhibitors

4/2024	The early-stage clinical course of anti-pituitary-specific transcription factor-1 hypophysitis diagnosed post-immune checkpoint inhibitor treatment: A case with review of literature.
2/2024	Effects of the Cortisol Milieu on Tumor-Infiltrating Immune Cells in Corticotroph Tumors.
1/2024	Fluctuations in plasma adrenocorticotropic hormone concentration may predict the onset of immune checkpoint inhibitor-related hypophysitis.
12/2023	Clinical features of anti-PIT-1 hypophysitis: A new aspect of paraneoplastic autoimmune condition.
1/2023	Combined Hypophysitis and Type 1 Diabetes Mellitus Related to Immune Checkpoint Inhibitors.
1/2023	Paraneoplastic isolated adrenocorticotropic hormone deficiency revealed after immune checkpoint inhibitors therapy: new insights into anti-corticotroph antibody.
12/2021	Mechanistic insights into immune checkpoint inhibitor-related hypophysitis: a form of paraneoplastic syndrome.
1/2018	Two Cases of Atezolizumab-Induced Hypophysitis.

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Genzo Iguchi Research Topics

Disease

18	Neoplasms (Cancer) 04/2024 - 03/2004
10	Hypophysitis 04/2024 - 10/2015
9	Acromegaly 11/2023 - 01/2008
9	Hypothyroidism 12/2021 - 06/2003
7	Autoimmune Hypophysitis 11/2019 - 01/2014
4	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 04/2024 - 10/2018
4	Pheochromocytoma 01/2024 - 03/2004
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2023 - 01/2014
4	Cushing Syndrome 01/2022 - 01/2014
4	Non-alcoholic Fatty Liver Disease 01/2018 - 06/2012
3	Thymoma (Thymic Carcinoma) 01/2024 - 01/2020
3	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2024 - 01/2018
3	Carcinoma (Carcinomatosis) 01/2023 - 10/2018
3	Adrenocortical Adenoma (Disease, Conn's) 01/2022 - 01/2017
3	Autoimmune Diseases (Autoimmune Disease) 03/2021 - 01/2014
3	Inflammation (Inflammations) 10/2016 - 09/2009
3	Combined Pituitary Hormone Deficiency 04/2015 - 11/2008
3	Muscular Atrophy (Muscle Atrophy) 09/2012 - 06/2010
2	Disease Progression 04/2024 - 02/2019
2	Pituitary Neoplasms (Pituitary Adenoma) 02/2024 - 01/2003
2	ACTH-Secreting Pituitary Adenoma 02/2024 - 01/2017
2	Paraganglioma (Paragangliomas) 01/2024 - 01/2017
2	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 10/2022 - 10/2015
2	Adenoma (Adenomas) 09/2020 - 01/2003
2	Atrophy 01/2018 - 06/2010
2	Malnutrition (Nutritional Deficiencies) 01/2018 - 09/2013
2	Insulin Resistance 01/2017 - 06/2010
2	Obesity 01/2016 - 01/2013
2	Carcinogenesis 08/2012 - 09/2009
2	Hypertension (High Blood Pressure) 04/2012 - 08/2008
1	Stomach Neoplasms (Stomach Cancer) 04/2024
1	Lymphatic Metastasis 04/2024
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2024
1	Thyroiditis 01/2024
1	COVID-19 01/2023
1	Disease Susceptibility (Diathesis) 01/2023
1	Neoplasm Metastasis (Metastasis) 01/2023
1	Adrenocorticotropic hormone deficiency 01/2023
1	Pituitary ACTH Hypersecretion 06/2022
1	Hyperaldosteronism (Conn Syndrome) 01/2022
1	Hyperplasia 01/2020
1	Leiomyoma (Uterine Fibroids) 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2020
1	Leiomyomatosis 01/2020
1	Myxoma (Myxomas) 01/2020
1	Parathyroid Neoplasms (Parathyroid Neoplasm) 10/2019

Drug/Important Bio-Agent (IBA)

17	Growth Hormone (Somatotropin)IBA 04/2024 - 01/2011
14	Insulin-Like Growth Factor I (IGF-1)IBA 11/2023 - 01/2008
11	ProlactinIBA 04/2024 - 06/2003
11	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 04/2024 - 01/2011
9	Proteins (Proteins, Gene)FDA Link 03/2021 - 01/2003
8	Immune Checkpoint InhibitorsIBA 04/2024 - 01/2018
7	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2024 - 01/2018
7	Transcription Factors (Transcription Factor)IBA 12/2023 - 03/2004
7	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 01/2008
6	Hydrocortisone (Cortisol)FDA LinkGeneric 02/2024 - 01/2014
4	AntibodiesIBA 01/2023 - 09/2014
4	Isolated ACTH DeficiencyIBA 01/2023 - 02/2014
3	LigandsIBA 11/2023 - 01/2018
3	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2023 - 01/2020
3	Insulin (Novolin)FDA Link 09/2022 - 06/2010
3	Transcription Factor Pit-1 (Transcription Factor Pit 1)IBA 01/2017 - 06/2003
3	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2012 - 06/2010
2	Hormones (Hormone)IBA 04/2024 - 10/2018
2	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2024 - 08/2015
2	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2024 - 08/2015
2	Octreotide (Sandostatin)FDA LinkGeneric 11/2023 - 01/2013
2	GlucocorticoidsIBA 01/2023 - 02/2019
2	Insulin-Like PeptidesIBA 01/2016 - 06/2012
2	Immunoglobulin G (IgG)IBA 10/2015 - 02/2014
2	AutoantibodiesIBA 04/2015 - 01/2014
2	Indicators and Reagents (Reagents)IBA 01/2014 - 09/2012
2	Branched-Chain Amino AcidsIBA 09/2012 - 06/2010
2	UbiquitinIBA 09/2012 - 03/2004
2	AntioxidantsIBA 03/2011 - 06/2010
1	NivolumabIBA 04/2024
1	Capecitabine (Xeloda)FDA Link 04/2024
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2024
1	Metyrapone FDA Link 02/2024
1	Doxazosin (Cardura)FDA LinkGeneric 01/2024
1	alpha-Methyltyrosine (Metirosine)FDA Link 01/2024
1	Thyroid HormonesIBA 01/2024
1	Therapeutic UsesIBA 11/2023
1	Somatostatin Receptors (Somatostatin Receptor)IBA 11/2023
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2023
1	Vasopressins (Vasopressin)IBA 10/2022
1	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 06/2022
1	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 01/2022
1	Cytochrome P450 Family 11IBA 01/2022
1	AntigensIBA 12/2021
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 12/2021
1	AutoantigensIBA 12/2021
1	ReninIBA 09/2020
1	Adrenergic Receptors (Adrenergic Receptor)IBA 09/2020
1	AldosteroneIBA 09/2020
1	Fumarate Hydratase (Fumarase)IBA 01/2020
1	S-(2-succinyl)cysteineIBA 01/2020
1	EpitopesIBA 11/2019

Therapy/Procedure

10	Therapeutics 04/2024 - 07/2012
3	Immunotherapy 02/2024 - 01/2018